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Cell Growth, Proliferation and Cancer
Code:
BIOL-412
Semester:
Winter Semester
Course type:
Selection
Special notes:
Για τη λήψη του παραπάνω μαθήματος συνιστάται η επιτυχής παρακολούθηση των υποχρεωτικών μαθημάτων Κυτταρική Βιολογία, Μοριακή Βιολογία, Γενετική Ι και Γενετική ΙΙ.
Course website:
Course units:
3
ECTS units:
4
Hours per week
Theory:
3
Instructors
Description
Objectives of the course (preferably expressed in terms of learning outcomes and competences): To understand the cell biology of carcinogenesis and learn about recent advances in cancer therapy.
Course contents: Introduction in tumourigenesis: proto-oncogenes, oncogenes and oncosupressors; mutagenesis, immortalisation and carcinogenesis; cell cycle control in vertebrate cells; The mitotic spindle checkpoint; Membrane receptors and signal transduction pathways: the ERK, JNK p38MAPK and PI3 kinase pathways; Chromatin remodelling in carcinogenesis; DNA damage and responses; DNA repair pathways: mismatch repair, nucleotide excision repair, base excision repair, homologous recombination and non-homologous end-joining; Programmed cell death; Replicative senescence; Recent advances in cancer therapy.
Undergraduate Announcements
30/09/2019 - 10:03
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25/10/2018 - 10:11
15/10/2018 - 15:31
13/02/2017 - 12:41
Undergraduate courses
Biology department
The Department of Biology of the University of Crete was established in 1981 and is today an internationally recognized center for contemporary university education and research in the field of Biology.
University of Crete, Voutes University Campus, GR-70013,P.O.Box 2208, Heraklion, Crete, Greece
Tel.: +30 2810 394400-3, Fax: +30 2810 394404,
E-mail: secbio@uoc.gr
Tel.: +30 2810 394400-3, Fax: +30 2810 394404,
E-mail: secbio@uoc.gr