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Description
Course: BIO 501
Course: BIO 502
Course: BIO 503
Course: BIO 504
Course: BIO 505
Course: BIO 506
Course: BIO 507
Course: BIO 508
 

COURSE: ΒΙΟ 505
 
BIOINFORMATICS
Coordinators: M. Kokkinidis- N. Kyrpides Credit hours: 20
DECEMBER 2004
CONTENTS INSTRUCTOR DURATION
Unit 0: ΑVAILABLE TOOLS FOR BIOINFORMATICS M.Kokkinidis
A. Economou
2 hours
Unit 1: Introduction
Overview of Bioinformatics
The scope of Bioinformatics
Bioinformatics and the Internet
Hans-Peter Klenk 2 hours
Unit 2: Principles and Methods of Sequence Analysis Analysis of raw sequence data
Principles of Gene Finding
Principles of sequence similarity (Blast, FastA, etc)
Principles of multiple sequence alignment
Functional classification of genes and proteins (GO terms)
Protein domain, motif and pattern searches
Hans-Peter Klenk 2 hours
Unit 3: Principles and Methods of Sequence Analysis (cont'd)
Methods for searching similar sequences
Principles and bioinformatics-applications of artificial neural networks
Principles and bioinformatics-applications of genetic algorithms
Martin Rezcko 2 hours
Unit 4: Information Sources for Genomics
General purpose sequence Databases
Protein sequence motif and domain databases
Protein structure databases
Organism specific databases
Taxonomy, Protein interactions and other databases
Nikos Kyrpides 2 hours
Unit 5: Genome Annotation and Analysis
Genome Projects
Tools and Methods
Genome context analysis
Nikos Kyrpides 2 hours
Unit 6: The ERGO genome analysis and discovery system
The ERGO Toolkit
Comparative Genomics through ERGO
Principles of Metabolic Reconstruction
Protein-protein interaction and functional network predictions
Nikos Kyrpides 4 hours
Unit 7: Comparative Genomics and Evolution
The tree of Life before and after the Genome
Phylogenetics
Evolutionary issues
Nikos Kyrpides 2 hours
Unit 8: Post-Genomics - Proteomics
Microarray data: analysis methods
Yiota Poirazi 2 hours
  TOTAL 20 Credit hours



 Last revision date: 16 June, 2004